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Recombinant Human Phosphofurin acidic cluster sorting protein 2 (PACS2), Truncated

ACP19521

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19521 Target NamePACS2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ86VP3
Background Information
  • Uniprot Id

    Q86VP3

  • Target Species

    Human

  • Target Name

    PACS2

  • Target Full Name

    Phosphofurin acidic cluster sorting protein 2

  • Target Function

    Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

  • Target Subcellular Location

    Endoplasmic reticulum. Mitochondrion.

  • Target Protein Families

    PACS family

  • Target Tissue Specificity

    Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis.

  • Target Synonyms

    6720425G15Rik; AW208651; AW489976; E230011J22; FLJ25488; KIAA0602; mKIAA0602; PACS 2; PACS-2; PACS1 like protein; PACS1-like protein; PACS1L; PACS2; PACS2_HUMAN; Phosphofurin acidic cluster sorting protein 1 like; Phosphofurin acidic cluster sorting protein 2

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