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| Cat.No | ACP03262 | Target Name | PIK3R5 |
|---|---|---|---|
| Target Synonyms | 5 bisphosphate 3 kinase regulatory subunit; Phosphoinositide 3 kinase, 5-bisphosphate 3-kinase regulatory subunit; F730038I15Rik; FOAP 2; FOAP2; OTTHUMP00000135339; p101; P101 PI3K; p101-PI3K; Phosphatidylinositol 4; Phosphatidylinositol 4, p101; Phosphoinositide 3 kinase, regulatory subunit, regulatory subunit 5, regulatory subunit 5; Phosphoinositide 3 kinase | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-494aa |
| Mol Weight | 70.9kDa | Protein Length | Full Length of Isoform 2 |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WYR1 |
|---|
Uniprot Id
Q8WYR1
Target Species
Human
Target Name
PIK3R5
Target Full Name
Phosphoinositide 3-kinase regulatory subunit 5
Target Function
Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG.
Target Involvement
Ataxia-oculomotor apraxia 3 (AOA3)
Target Subcellular Location
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein.
Target Tissue Specificity
Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli.
Target Research Area
Signal Transduction
Target Synonyms
5-bisphosphate 3-kinase regulatory subunit; F730038I15Rik; FOAP 2; FOAP2; OTTHUMP00000135339; p101; P101 PI3K; p101-PI3K; Phosphatidylinositol 4; Phosphatidylinositol 4,5 bisphosphate 3 kinase regulatory subunit; Phosphoinositide 3 kinase, regulatory subunit 5; Phosphoinositide 3 kinase, regulatory subunit 5, p101; Phosphoinositide 3 kinase, regulatory subunit, polypeptide p101; Phosphoinositide 3-kinase regulatory subunit 5; PI3 kinase p101 subunit; PI3 kinase regulatory subunit 5; PI3-kinase p101 subunit; PI3-kinase regulatory subunit 5; PI3R5_HUMAN; PIK3 R5; PIK3R5; Protein FOAP 2; Protein FOAP-2; PtdIns 3 kinase p101; PtdIns 3 kinase regulatory subunit; PtdIns-3-kinase p101; PtdIns-3-kinase regulatory subunit
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