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| Cat.No | ACP18028 | Target Name | PDGFRL |
|---|---|---|---|
| Target Synonyms | PDGF receptor beta like tumor suppressor ; PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Pdgfrl; PDGRL; PGFRL_HUMAN; Platelet-derived growth factor receptor-like protein; PRLTS | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 22-375 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q15198 |
|---|
Uniprot Id
Q15198
Target Species
Human
Target Name
PDGFRL
Target Full Name
Platelet-derived growth factor receptor-like protein
Target Involvement
Colorectal cancer (CRC)
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed in colon, lung and liver.
Target Synonyms
PDGF receptor beta like tumor suppressor ; PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Pdgfrl; PDGRL; PGFRL_HUMAN; Platelet-derived growth factor receptor-like protein; PRLTS
Target Background
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
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