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| Cat.No | ACP19544 | Target Name | PMF1 |
|---|---|---|---|
| Target Synonyms | NNF1R; PMF 1; PMF-1; Pmf1; PMF1_HUMAN; Polyamine modulated factor 1; Polyamine-modulated factor 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-205 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6P1K2 |
|---|
Uniprot Id
Q6P1K2
Target Species
Human
Target Name
PMF1
Target Full Name
Polyamine-modulated factor 1
Target Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
Target Subcellular Location
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Target Tissue Specificity
Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver.
Target Synonyms
NNF1R; PMF 1; PMF-1; Pmf1; PMF1_HUMAN; Polyamine modulated factor 1; Polyamine-modulated factor 1
Target Background
Enables leucine zipper domain binding activity and transcription coactivator activity. Involved in chromosome segregation. Located in Golgi apparatus; kinetochore; and nucleoplasm. Part of MIS12/MIND type complex. Implicated in bladder carcinoma and urinary bladder cancer.
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