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Recombinant Human Polyamine-modulated factor 1 (PMF1)

ACP19544

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19544 Target NamePMF1
Target SynonymsNNF1R; PMF 1; PMF-1; Pmf1; PMF1_HUMAN; Polyamine modulated factor 1; Polyamine-modulated factor 1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range2-205
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6P1K2
Background Information
  • Uniprot Id

    Q6P1K2

  • Target Species

    Human

  • Target Name

    PMF1

  • Target Full Name

    Polyamine-modulated factor 1

  • Target Function

    Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.

  • Target Subcellular Location

    Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.

  • Target Tissue Specificity

    Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver.

  • Target Synonyms

    NNF1R; PMF 1; PMF-1; Pmf1; PMF1_HUMAN; Polyamine modulated factor 1; Polyamine-modulated factor 1

  • Target Background

    Enables leucine zipper domain binding activity and transcription coactivator activity. Involved in chromosome segregation. Located in Golgi apparatus; kinetochore; and nucleoplasm. Part of MIS12/MIND type complex. Implicated in bladder carcinoma and urinary bladder cancer.

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