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Recombinant Human Potassium channel subfamily T member 1 (KCNT1), Truncated

ACP06145

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06145 Target NameKCNT1
Target SynonymsbA100C15.2; EIEE14; ENFL5; KCa4.1; KCNT1; KCNT1_HUMAN; Potassium channel subfamily T member 1; Potassium channel, member 1 ; Sequence like a calcium-activated K+ channel; SLACK ; Slo2.2, member 1; Potassium channel, sodium activated subfamily T, subfamily TFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5JUK3
Background Information
  • Uniprot Id

    Q5JUK3

  • Target Species

    Human

  • Target Name

    KCNT1

  • Target Full Name

    Potassium channel subfamily T member 1

  • Target Function

    Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro).

  • Target Involvement

    Epileptic encephalopathy, early infantile, 14 (EIEE14); Epilepsy, nocturnal frontal lobe, 5 (ENFL5)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa4.1/KCNT1 sub-subfamily

  • Target Tissue Specificity

    Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.

  • Target Synonyms

    bA100C15.2; EIEE14; ENFL5; KCa4.1; KCNT1; KCNT1_HUMAN; Potassium channel subfamily T member 1; Potassium channel, sodium activated subfamily T, member 1; Potassium channel, subfamily T, member 1 ; Sequence like a calcium-activated K+ channel; SLACK ; Slo2.2

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