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| Cat.No | ACP24618 | Target Name | POU6F2 |
|---|---|---|---|
| Target Synonyms | POU6F2; RPF1; POU domain; class 6; transcription factor 2; Retina-derived POU domain factor 1; RPF-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-691 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P78424 |
|---|
Uniprot Id
P78424
Target Species
Human
Target Name
POU6F2
Target Full Name
POU domain, class 6, transcription factor 2
Target Function
Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA.
Target Involvement
Hereditary susceptibility to Wilms tumor 5 (WT5)
Target Subcellular Location
Nucleus.
Target Protein Families
POU transcription factor family, Class-6 subfamily
Target Tissue Specificity
Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina.
Target Synonyms
POU6F2; RPF1; POU domain; class 6; transcription factor 2; Retina-derived POU domain factor 1; RPF-1
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