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Recombinant Human POU domain, class 6, transcription factor 2 (POU6F2)

ACP24618

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP24618 Target NamePOU6F2
Target SynonymsPOU6F2; RPF1; POU domain; class 6; transcription factor 2; Retina-derived POU domain factor 1; RPF-1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-691
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP78424
Background Information
  • Uniprot Id

    P78424

  • Target Species

    Human

  • Target Name

    POU6F2

  • Target Full Name

    POU domain, class 6, transcription factor 2

  • Target Function

    Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA.

  • Target Involvement

    Hereditary susceptibility to Wilms tumor 5 (WT5)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    POU transcription factor family, Class-6 subfamily

  • Target Tissue Specificity

    Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina.

  • Target Synonyms

    POU6F2; RPF1; POU domain; class 6; transcription factor 2; Retina-derived POU domain factor 1; RPF-1

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