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| Cat.No | ACP04912 | Target Name | PRDM15 |
|---|---|---|---|
| Target Synonyms | PRDM15; C21orf83; ZNF298; PR domain zinc finger protein 15; EC 2.1.1.-; PR domain-containing protein 15; Zinc finger protein 298 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P57071 |
|---|
Uniprot Id
P57071
Target Species
Human
Target Name
PRDM15
Target Full Name
PR domain zinc finger protein 15
Target Function
Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development. Plays also a role in induced pluripotent stem cells (iPSCs) reprogramming
Target Subcellular Location
Nucleus.
Target Protein Families
Class V-like SAM-binding methyltransferase superfamily
Target Tissue Specificity
Detected in all tissues examined.
Target Synonyms
PRDM15; C21orf83; ZNF298; PR domain zinc finger protein 15; EC 2.1.1.-; PR domain-containing protein 15; Zinc finger protein 298
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