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| Cat.No | ACP12453 | Target Name | PRPF18 |
|---|---|---|---|
| Target Synonyms | PRPF18; HPRP18Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-342 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q99633 |
|---|
Uniprot Id
Q99633
Target Species
Human
Target Name
PRPF18
Target Full Name
Pre-mRNA-splicing factor 18
Target Function
Participates in the second step of pre-mRNA splicing.
Target Subcellular Location
Nucleus speckle.
Target Protein Families
PRP18 family
Target Synonyms
PRPF18; HPRP18Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18
Target Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.
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