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| Cat.No | ACP22577 | Target Name | VBP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-197 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P61758 |
|---|
Uniprot Id
P61758
Target Species
Human
Target Name
VBP1
Target Full Name
Prefoldin subunit 3
Target Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Target Subcellular Location
Cytoplasm. Nucleus. Note=In complex with VHL can translocate to the nucleus.
Target Protein Families
Prefoldin subunit alpha family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
HIBBJ 46; HIBBJ46; PFD 3; PFD3; PFD3_HUMAN; PFDN 3; PFDN3; Prefoldin 3; Prefoldin subunit 3; Prefoldin3; VBP 1; VBP-1; VBP1; VHL binding protein 1; VHL-binding protein 1; Von Hippel Lindau binding protein 1; Von Hippel-Lindau-binding protein 1
Target Background
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms.
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