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| Cat.No | ACP14975 | Target Name | DDX60 |
|---|---|---|---|
| Target Synonyms | DDX60; DDX60_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 60; DEAD box protein 60; Probable ATP-dependent RNA helicase DDX60 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IY21 |
|---|
Uniprot Id
Q8IY21
Target Species
Human
Target Name
DDX60
Target Full Name
Probable ATP-dependent RNA helicase DDX60
Target Function
Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV).
Target Subcellular Location
Cytoplasm.
Target Protein Families
Helicase family
Target Tissue Specificity
Brain, lymph node, prostate, stomach, thyroid, tongue, trachea, uterus, skeletal muscle, spleen, kidney, liver and small intestine.
Target Research Area
Others
Target Synonyms
DDX60; DDX60_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 60; DEAD box protein 60; Probable ATP-dependent RNA helicase DDX60
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