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Recombinant Human Probable cytosolic iron-sulfur protein assembly protein CIAO1 (CIAO1)

ACP04111

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Specifications

Cat.No	ACP04111	Target Name	CIAO1
Target Synonyms	CIAO1; CIA1; WDR39Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-339aa
Mol Weight	53.8kDa	Protein Length	Full length
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O76071

Background Information

Uniprot Id

O76071
Target Species

Human
Target Name

CIAO1
Target Full Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1
Target Function

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Target Subcellular Location

Cytoplasm.
Target Protein Families

WD repeat CIA1 family
Target Research Area

Transcription
Target Synonyms

CIAO1; CIA1; WDR39Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39
Target Background

Involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Located in cytoplasm. Part of CIA complex and MMXD complex.

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Recombinant Human Probable cytosolic iron-sulfur protein assembly protein CIAO1 (CIAO1)

Specifications

Immunogen Information

Inquire Recombinant Human Probable cytosolic iron-sulfur protein assembly protein CIAO1 (CIAO1) Now

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