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| Cat.No | ACP08076 | Target Name | ADGRG5 |
|---|---|---|---|
| Target Synonyms | ADGRG5; GPR114; PGR27; UNQ2524/PRO6017; Adhesion G-protein coupled receptor G5; G-protein coupled receptor 114; G-protein coupled receptor PGR27 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IZF4 |
|---|
Uniprot Id
Q8IZF4
Target Species
Human
Target Name
ADGRG5
Target Full Name
Adhesion G-protein coupled receptor G5
Target Function
Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway. Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking).
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Tissue Specificity
Expressed in immune cells. Primarily found in granulocytes. Found in eosinophils.
Target Synonyms
ADGRG5; GPR114; PGR27; UNQ2524/PRO6017; Adhesion G-protein coupled receptor G5; G-protein coupled receptor 114; G-protein coupled receptor PGR27
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