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| Cat.No | ACP22128 | Target Name | PDYN |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 175-184 | Protein Length | Cytoplasmic Domain |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P01213 |
|---|
Uniprot Id
P01213
Target Species
Human
Target Name
PDYN
Target Full Name
Proenkephalin-B
Target Function
Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.; Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.; Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
Target Involvement
Spinocerebellar ataxia 23 (SCA23)
Target Subcellular Location
Secreted.
Target Protein Families
Opioid neuropeptide precursor family
Target Synonyms
ADCA; Alpha neoendorphin; Beta neoendorphin; Beta-neoendorphin-dynorphin; Big Dyn; Big dynorphin; Dyn; Dyn-A17; Dyn-B; Dynorphin A; Dynorphin A(1-13); Dynorphin A(1-17); Dynorphin A(1-8); Dynorphin B; Dynorphin B(1-13); Dynorphin B-29; Enkephalin B; Leu enkephalin; Leumorphin; Neoendorphin dynorphin enkephalin prepropeptide; PDYN; PDYN_HUMAN; PENKB; Preprodynorphin; Preproenkephalin B; Prodynorphin; Proenkephalin B; Rimorphin; SCA23
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