Recombinant Human Proline-rich acidic protein 1 (PRAP1)

Cat.No	ACP19200	Target Name	PRAP1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	21-151	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP19200

Target Name

PRAP1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

21-151

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q96NZ9

Background Information

Uniprot Id

Q96NZ9
Target Species

Human
Target Name

PRAP1
Target Full Name

Proline-rich acidic protein 1
Target Function

Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. Protects the gastrointestinal epithelium from irradiation-induced apoptosis. May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May downregulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas.
Target Subcellular Location

Secreted. Endoplasmic reticulum.
Target Tissue Specificity

Highly expressed in the intestinal epithelial cells (at protein level). Abundantly expressed in the epithelial cells of the liver, kidney and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the
Target Synonyms

Epididymis tissue protein Li 178; MGC126792; OTTHUMP00000020800; Prap1; PRAP1_HUMAN; PRO1195; Proline rich acidic protein 1 ; Proline-rich acidic protein 1; RP11 122K13.6 ; UNQ608/PRO1195; UPA; Uterine specific proline rich acidic protein ; Uterine specific proline rich acidic protein UPA; Uterine-specific proline-rich acidic protein
Target Background

Predicted to enable triglyceride binding activity. Involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; deactivation of mitotic spindle assembly checkpoint; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and extracellular region.

Recombinant Human Proline-rich acidic protein 1 (PRAP1)

Specifications

Immunogen Information

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