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Recombinant Human Proline-rich protein 7 (PRR7), Truncated

ACP14228

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14228 Target NamePRR7
Target SynonymsProline rich protein 7; Proline-rich protein 7; Prr7; PRR7_HUMAN; Synaptic proline rich membrane protein; Synaptic proline-rich membrane protein; transmembrane adaptor protein 3; TRAP3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TB68
Background Information
  • Uniprot Id

    Q8TB68

  • Target Species

    Human

  • Target Name

    PRR7

  • Target Full Name

    Proline-rich protein 7

  • Target Function

    Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner. Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN. Might play a redundant role in the regulation of T cell receptor signaling. Might promote apoptosis in T cells.

  • Target Subcellular Location

    Cell membrane; Single-pass type III membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type III membrane protein. Cell junction, synapse, postsynaptic density membrane. Cytoplasm, perinuclear region. Cell junction, synapse. Cell projection, dendrite. Nucleus.

  • Target Tissue Specificity

    Strongly expressed in brain tissue including the hippocampus, and moderately expressed in esophagus, trachea, lung, ovary, cervix, prostate, testes, thyroid, thymus, lymph nodes and peripheral blood lymphocytes.

  • Target Synonyms

    Proline rich protein 7; Proline-rich protein 7; Prr7; PRR7_HUMAN; Synaptic proline rich membrane protein; Synaptic proline-rich membrane protein; transmembrane adaptor protein 3; TRAP3

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