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| Cat.No | ACP15033 | Target Name | APCDD1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8J025 |
|---|
Uniprot Id
Q8J025
Target Species
Human
Target Name
APCDD1
Target Full Name
Protein APCDD1
Target Function
Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
Target Involvement
Hypotrichosis 1 (HYPT1)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
APCDD1 family
Target Tissue Specificity
Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. Abundantly expressed in both the epidermal and dermal compartments of the hair follicle. Present in
Target Synonyms
Adenomatosis polyposis coli down regulated 1; Adenomatosis polyposis coli down regulated 1 protein; Adenomatosis polyposis coli down-regulated 1 protein; APCD1_HUMAN; APCDD 1; APCDD1; B7323; DRAPC1; FP7019; HHS; HTS; hypoptrichosis simplex; Protein APCDD1
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