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| Cat.No | ACP22615 | Target Name | BTG1 |
|---|---|---|---|
| Target Synonyms | BTG1Protein BTG1; B-cell translocation gene 1 protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-171 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P62324 |
|---|
Uniprot Id
P62324
Target Species
Human
Target Name
BTG1
Target Full Name
Protein BTG1
Target Function
Anti-proliferative protein.
Target Involvement
A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC.
Target Protein Families
BTG family
Target Synonyms
BTG1Protein BTG1; B-cell translocation gene 1 protein
Target Background
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
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