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| Cat.No | ACP13307 | Target Name | DDI1 |
|---|---|---|---|
| Target Synonyms | DDI1Protein DDI1 homolog 1; EC 3.4.23.- | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-396 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WTU0 |
|---|
Uniprot Id
Q8WTU0
Target Species
Human
Target Name
DDI1
Target Full Name
Protein DDI1 homolog 1
Target Function
Probable aspartic protease (Probable). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable). Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity.
Target Protein Families
DDI1 family
Target Synonyms
DDI1Protein DDI1 homolog 1; EC 3.4.23.-
Target Background
Predicted to enable aspartic-type endopeptidase activity. Involved in several processes, including cellular response to hydroxyurea; proteasomal protein catabolic process; and regulation of DNA stability.
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