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Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP)

ACP01277

Number
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Specifications


Cat.No ACP01277 Target NameTIPARP
FormLiquid or Lyophilized powderExpression SystemE.coli
Expression Range1-657aaMol Weight82.2 kDa
Protein LengthFull lengthPurityGreater than 85% as determined by SDS-PAGE.
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ7Z3E1
Background Information
  • Uniprot Id

    Q7Z3E1

  • Target Species

    Human

  • Target Name

    TIPARP

  • Target Full Name

    Protein mono-ADP-ribosyltransferase TIPARP

  • Target Function

    ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR.

  • Target Subcellular Location

    Nucleus.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; AW558171; DDF1; DKFZp434J214; DKFZp686N0351; DKFZp686P1838; FLJ40466; PARP 1; PARP 7; PARP-7; PARPT_HUMAN; pART14; Poly [ADP ribose] polymerase 7; Poly [ADP-ribose] polymerase 7; TCDD inducible poly(ADP ribose) polymerase; TCDD-inducible poly [ADP-ribose] polymerase; TIPARP

  • Target Background

    This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants.

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