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| Cat.No | ACP13200 | Target Name | WDYHV1 |
|---|---|---|---|
| Target Synonyms | WDYHV1; C8orf32; NTAQ1; Protein N-terminal glutamine amidohydrolase; EC 3.5.1.122; Protein NH2-terminal glutamine deamidase; N-terminal Gln amidase; Nt(Q)-amidase; WDYHV motif-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-205 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96HA8 |
|---|
Uniprot Id
Q96HA8
Target Species
Human
Target Name
NTAQ1
Target Full Name
Protein N-terminal glutamine amidohydrolase
Target Function
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
NTAQ1 family
Target Synonyms
WDYHV1; C8orf32; NTAQ1; Protein N-terminal glutamine amidohydrolase; EC 3.5.1.122; Protein NH2-terminal glutamine deamidase; N-terminal Gln amidase; Nt(Q)-amidase; WDYHV motif-containing protein 1
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