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| Cat.No | ACP14607 | Target Name | PPM1K |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 30-372 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N3J5 |
|---|
Uniprot Id
Q8N3J5
Target Species
Human
Target Name
PPM1K
Target Full Name
Protein phosphatase Mn(2+)-dependent 1K
Target Function
Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development.
Target Involvement
Maple syrup urine disease, mild variant (MSUDMV)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
PP2C family
Target Synonyms
BDP; mitochondrial; MSUDMV; PP2C domain containing protein phosphatase 1K; PP2C domain-containing protein phosphatase 1K; PP2C kappa; PP2C like mitochondrial protein; PP2C type mitochondrial phosphoprotein phosphatase; PP2C-kappa; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PP2Ckappa; PP2CM; PPM1K; PPM1K_HUMAN; Protein phosphatase 1K; Protein phosphatase 1K; mitochondrial; Protein phosphatase 2C isoform kappa; Protein phosphatase Mg2+/Mn2+ dependent 1K; PTMP; UG0882E07
Target Background
This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.
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