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| Cat.No | ACP14172 | Target Name | SSH1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WYL5 |
|---|
Uniprot Id
Q8WYL5
Target Species
Human
Target Name
SSH1
Target Full Name
Protein phosphatase Slingshot homolog 1
Target Function
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion. Also localized to the cleavage furrow and the midbody during cytokinesis.
Target Protein Families
Protein-tyrosine phosphatase family
Target Synonyms
AW551225; Coro1c; coronin; actin binding protein 1C; Gm1394; Gm1395; hSSH-1L; mSSH 1L; OTTMUSP00000031415; Protein phosphatase Slingshot homolog 1; Slingshot 1; slingshot 1L; slingshot homolog 1; slingshot like 1; Slingshot1; SSH 1; SSH 1L; SSH-1L; SSH-like protein 1; Ssh1; SSH1_HUMAN
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