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| Cat.No | ACP15750 | Target Name | SHISA6 |
|---|---|---|---|
| Target Synonyms | SHISA6; Protein shisa-6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZSJ9 |
|---|
Uniprot Id
Q6ZSJ9
Target Species
Human
Target Name
SHISA6
Target Full Name
Protein shisa-6
Target Function
Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density.
Target Protein Families
Shisa family
Target Tissue Specificity
Expressed in the developing ventral mesencephalon.
Target Synonyms
SHISA6; Protein shisa-6
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