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| Cat.No | ACP11831 | Target Name | UNC45A |
|---|---|---|---|
| Target Synonyms | UNC45A; SMAP1; Protein unc-45 homolog A; Unc-45A; GCUNC-45; Smooth muscle cell-associated protein 1; SMAP-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H3U1 |
|---|
Uniprot Id
Q9H3U1
Target Species
Human
Target Name
UNC45A
Target Full Name
Protein unc-45 homolog A
Target Function
Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen.
Target Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Predominant in the perinuclear region. Little protein in the nucleus.
Target Tissue Specificity
Detected in peripheral blood leukocytes, bone marrow, adrenal gland, trachea, spinal cord, thyroid, lymph node and stomach.
Target Synonyms
UNC45A; SMAP1; Protein unc-45 homolog A; Unc-45A; GCUNC-45; Smooth muscle cell-associated protein 1; SMAP-1
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