Home Products Recombinant Human Protein VAC14 homolog (VAC14), Truncated

Recombinant Human Protein VAC14 homolog (VAC14), Truncated

ACP18603

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP18603	Target Name	VAC14
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q08AM6

Background Information

Uniprot Id

Q08AM6
Target Species

Human
Target Name

VAC14
Target Full Name

Protein VAC14 homolog
Target Function

Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
Target Involvement

Striatonigral degeneration, childhood-onset (SNDC)
Target Subcellular Location

Endosome membrane. Microsome membrane. Note=Mainly associated with membranes of the late endocytic pathway.
Target Protein Families

VAC14 family
Target Tissue Specificity

Ubiquitously expressed.
Target Synonyms

ArPIKfyve; FLJ10305; FLJ36622; FLJ46582; MGC149815; MGC149816; OTTHUMP00000174908; Protein VAC14 homolog; Tax1 (human T cell leukemia virus type I) binding protein 1; Tax1 (human T cell leukemia virus type I) binding protein 2; Tax1 binding protein 2; Tax1-binding protein 2; TAX1BP2; TRX; VAC 14; vac14; Vac14 homolog (S. cerevisiae); Vac14 homolog; VAC14_HUMAN

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Recombinant Human Protein VAC14 homolog (VAC14), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Protein VAC14 homolog (VAC14), Truncated Now

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