Home Products Recombinant Human Putative RNA-binding protein 11 (RBM11)

Recombinant Human Putative RNA-binding protein 11 (RBM11)

ACP22772

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Specifications

Cat.No	ACP22772	Target Name	RBM11
Target Synonyms	RBM11; Splicing regulator RBM11; RNA-binding motif protein 11	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-281
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P57052

Background Information

Uniprot Id

P57052
Target Species

Human
Target Name

RBM11
Target Full Name

Splicing regulator RBM11
Target Function

Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.
Target Subcellular Location

Nucleus, nucleoplasm. Nucleus speckle. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles.
Target Tissue Specificity

Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain.
Target Synonyms

RBM11; Splicing regulator RBM11; RNA-binding motif protein 11
Target Background

Enables poly(U) RNA binding activity and protein homodimerization activity. Acts upstream of or within cellular response to oxidative stress and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck.

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Recombinant Human Putative RNA-binding protein 11 (RBM11)

Specifications

Immunogen Information

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