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Recombinant Human PWWP domain-containing protein MUM1 (MUM1)

ACP17623

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17623 Target NameMUM1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-710Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ2TAK8
Background Information
  • Uniprot Id

    Q2TAK8

  • Target Species

    Human

  • Target Name

    PWWP3A

  • Target Full Name

    PWWP domain-containing DNA repair factor 3A

  • Target Function

    Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

  • Target Subcellular Location

    Nucleus. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.

  • Target Protein Families

    MUM1 family

  • Target Synonyms

    EXPAND1; FLJ14868; FLJ22283 ; HSPC211 ; Melanoma associated antigen (mutated) 1; Melanoma ubiquitous mutated protein; MGC131891; MGC163315; MUM 1; MUM-1; MUM1; MUM1_HUMAN; Mutated melanoma associated antigen 1; Mutated melanoma-associated antigen 1; Protein expandere; PWWP domain containing protein MUM1; PWWP domain-containing protein MUM1

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