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Recombinant Human Pyrin domain-containing protein 2 (PYDC2)

ACP17283

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17283 Target NamePYDC2
Target SynonymsPYDC2; POP2; Pyrin domain-containing protein 2; Pyrin-only protein 2; cellular POP2; cPOP2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-97
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ56P42
Background Information
  • Uniprot Id

    Q56P42

  • Target Species

    Human

  • Target Name

    PYDC2

  • Target Full Name

    Pyrin domain-containing protein 2

  • Target Function

    May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome. May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Tissue Specificity

    Predominantly expressed in peripheral blood. Weakly expressed in testis.

  • Target Synonyms

    PYDC2; POP2; Pyrin domain-containing protein 2; Pyrin-only protein 2; cellular POP2; cPOP2

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