Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The creation of the recombinant Human MRAS protein is achieved through genetic engineering techniques. A specific DNA sequence coding for the Human MRAS protein (1-205aa) is integrated into an expression vector, which serves as a carrier for gene expression. This vector is then introduced into e.coli cells, which are cultured to facilitate the expression of the desired protein. The protein is fused with a N-terminal 10xHis tag and C-terminal Myc tag. The recombinant Human MRAS protein is subsequently purified using affinity purification, resulting in a purity level exceeding 85%, as verified by SDS-PAGE analysis.
The creation of the recombinant Human MRAS protein is achieved through genetic engineering techniques. A specific DNA sequence coding for the Human MRAS protein (1-205aa) is integrated into an expression vector, which serves as a carrier for gene expression. This vector is then introduced into e.coli cells, which are cultured to facilitate the expression of the desired protein. The protein is fused with a N-terminal 10xHis tag and C-terminal Myc tag. The recombinant Human MRAS protein is subsequently purified using affinity purification, resulting in a purity level exceeding 85%, as verified by SDS-PAGE analysis.
| Cat.No | ACP00995 | Target Name | MRAS |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-205aa | Mol Weight | 28.5 kDa |
| Protein Length | Full length | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14807 |
|---|
Uniprot Id
O14807
Target Species
Human
Target Name
MRAS
Target Full Name
Ras-related protein M-Ras
Target Function
Serves as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway.
Target Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side.
Target Protein Families
Small GTPase superfamily, Ras family
Target Tissue Specificity
Expression highly restricted to the brain and heart.
Target Research Area
Cancer
Target Synonyms
FLJ42964; M ras; M-ras; Mras; Muscle and microspikes Ras; Muscle RAS oncogene homolog; Muscle Ras oncogene homologue; Muscle Ras viral oncogene homolog; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; Ras-related protein M-Ras; Ras-related protein R-Ras3; RASM_HUMAN; Related Ras viral oncogene homolog 3; RRas3; XRas
Target Background
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
