Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP12640 | Target Name | RCN3 |
|---|---|---|---|
| Target Synonyms | EF-hand calcium binding domain; Reticulocalbin-3; RLP49; UNQ239/PRO272, EF-hand calcium-binding protein RLP49; RCN3; RCN3_HUMAN; reticulocalbin 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 21-328 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96D15 |
|---|
Uniprot Id
Q96D15
Target Species
Human
Target Name
RCN3
Target Full Name
Reticulocalbin-3
Target Function
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum. Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens. This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion.
Target Subcellular Location
Endoplasmic reticulum lumen.
Target Protein Families
CREC family
Target Tissue Specificity
Widely expressed.
Target Synonyms
EF-hand calcium-binding protein RLP49; RCN3; RCN3_HUMAN; reticulocalbin 3, EF-hand calcium binding domain; Reticulocalbin-3; RLP49; UNQ239/PRO272
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
