Home Products Recombinant Human Rho guanine nucleotide exchange factor 25 (ARHGEF25)

Recombinant Human Rho guanine nucleotide exchange factor 25 (ARHGEF25)

ACP15273

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Specifications

Cat.No	ACP15273	Target Name	ARHGEF25
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-580	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q86VW2

Background Information

Uniprot Id

Q86VW2
Target Species

Human
Target Name

ARHGEF25
Target Full Name

Rho guanine nucleotide exchange factor 25
Target Function

May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis.
Target Subcellular Location

Cell membrane. Cytoplasm, myofibril, sarcomere. Note=Highly colocalizes with actin regions.
Target Tissue Specificity

Isoform 1 and isoform 2 are highly expressed in excitable tissues, such as brain, heart and muscle. Also detected in kidney and liver.
Target Synonyms

ARHGEF25; ARHGP_HUMAN; GEFT ; Guanine nucleotide exchange factor GEFT; p63RhoGEF; RAC/CDC42 exchange factor; Rac/Cdc42/Rho exchange factor GEFT; Rho guanine nucleotide exchange factor 25; RhoA/RAC/CDC42 exchange factor; RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT

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Recombinant Human Rho guanine nucleotide exchange factor 25 (ARHGEF25)

Specifications

Immunogen Information

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