Recombinant Human RNA-binding motif, single-stranded-interacting protein 3 (RBMS3)

Uniprot Id

Q6XE24

Target Species

Human

Target Name

RBMS3

Target Full Name

RNA-binding motif, single-stranded-interacting protein 3

Target Function

Binds poly(A) and poly(U) oligoribonucleotides.

Target Subcellular Location

Cytoplasm.

Target Tissue Specificity

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Target Synonyms

RBMS3; RNA-binding motif; single-stranded-interacting protein 3

Target Background

This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.