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| Cat.No | ACP15907 | Target Name | RPUSD3 |
|---|---|---|---|
| Target Synonyms | RPUSD3; Mitochondrial mRNA pseudouridine synthase RPUSD3; EC 5.4.99.-; RNA pseudouridylate synthase domain-containing protein 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-351 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6P087 |
|---|
Uniprot Id
Q6P087
Target Species
Human
Target Name
RPUSD3
Target Full Name
Mitochondrial mRNA pseudouridine synthase RPUSD3
Target Function
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs), a post-transcriptional modification necessary for their translation. Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Pseudouridine synthase RluA family
Target Synonyms
RPUSD3; Mitochondrial mRNA pseudouridine synthase RPUSD3; EC 5.4.99.-; RNA pseudouridylate synthase domain-containing protein 3
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