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| Cat.No | ACP12630 | Target Name | SGF29 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-293 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96ES7 |
|---|
Uniprot Id
Q96ES7
Target Species
Human
Target Name
SGF29
Target Full Name
SAGA-associated factor 29
Target Function
Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival.
Target Subcellular Location
Nucleus.
Target Protein Families
SGF29 family
Target Synonyms
CCDC101; Coiled coil domain containing 101; Coiled coil domain containing protein 101; Coiled-coil domain-containing protein 101; FLJ32446; OTTMUSP00000030606; SAGA associated factor 29 homolog; SAGA-associated factor 29 homolog; SGF29_HUMAN; STAF36
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