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| Cat.No | ACP13641 | Target Name | NEK11 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-645 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NG66 |
|---|
Uniprot Id
Q8NG66
Target Species
Human
Target Name
NEK11
Target Full Name
Serine/threonine-protein kinase Nek11
Target Function
Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
Target Subcellular Location
Nucleus. Nucleus, nucleolus.
Target Protein Families
Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily
Target Tissue Specificity
Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
Target Synonyms
4932416N14Rik; FLJ23495; NEK11; NEK11_HUMAN; NEK11S/L; Never in mitosis A-related kinase 11; NIMA (never in mitosis gene a) related kinase 11; NIMA (never in mitosis gene a)- related kinase 11; NIMA related kinase 11L ; NIMA related kinase 11S; NIMA-related kinase 11; NimA-related protein kinase 11; Serine/threonine-protein kinase Nek11
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