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| Cat.No | ACP10800 | Target Name | SERTAD1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-236 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UHV2 |
|---|
Uniprot Id
Q9UHV2
Target Species
Human
Target Name
SERTAD1
Target Full Name
SERTA domain-containing protein 1
Target Function
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Target Synonyms
CDK4 binding protein p34SEI; CDK4 binding protein p34SEI1; CDK4-binding protein p34SEI1; SEI-1; SEI1; SERTA domain containing 1; SERTA domain-containing protein 1; SERTAD1; SRTD1_HUMAN; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP Br1; TRIP-Br1
Target Background
Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
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