Home Products Recombinant Human Sialic acid-binding Ig-like lectin 11 (SIGLEC11), Truncated

Recombinant Human Sialic acid-binding Ig-like lectin 11 (SIGLEC11), Truncated

ACP14335

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Specifications

Cat.No	ACP14335	Target Name	SIGLEC11
Target Synonyms	sialic acid binding Ig like lectin 11; sialic acid binding lectin 11; Sialic acid-binding Ig-like lectin 11; Sialic acid-binding lectin 11; SIG11_HUMAN; Siglec 11; Siglec-11; SIGLEC11	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96RL6

Background Information

Uniprot Id

Q96RL6
Target Species

Human
Target Name

SIGLEC11
Target Full Name

Sialic acid-binding Ig-like lectin 11
Target Function

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Target Subcellular Location

Membrane; Single-pass type I membrane protein.
Target Protein Families

Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
Target Tissue Specificity

Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia.
Target Synonyms

sialic acid binding Ig like lectin 11; sialic acid binding lectin 11; Sialic acid-binding Ig-like lectin 11; Sialic acid-binding lectin 11; SIG11_HUMAN; Siglec 11; Siglec-11; SIGLEC11

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Recombinant Human Sialic acid-binding Ig-like lectin 11 (SIGLEC11), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Sialic acid-binding Ig-like lectin 11 (SIGLEC11), Truncated Now

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