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Recombinant Human Single Ig IL-1-related receptor (SIGIRR), Truncated

ACP16491

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP16491	Target Name	SIGIRR
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6IA17

Background Information

Uniprot Id

Q6IA17
Target Species

Human
Target Name

SIGIRR
Target Full Name

Single Ig IL-1-related receptor
Target Function

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Target Subcellular Location

Membrane; Single-pass type III membrane protein.
Target Protein Families

Interleukin-1 receptor family
Target Tissue Specificity

Mainly expressed in epithelial tissues such as kidney, lung and gut.
Target Research Area

Immunology
Target Synonyms

Ig IL1 related receptor; MGC110992; SIGIR_HUMAN; SIGIRR; Single Ig IL 1 related receptor; Single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; Single Ig IL1R Related Molecule; Single immunoglobulin and toll interleukin 1 receptor (TIR) domain; Single immunoglobulin and toll interleukin 1 receptor domain; Single immunoglobulin domain containing IL1R related protein; Single immunoglobulin domain IL1R1 related; Single immunoglobulin domain-containing IL1R-related protein; TIR 8; TIR8; Toll/interleukin 1 receptor 8; Toll/interleukin-1 receptor 8

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Recombinant Human Single Ig IL-1-related receptor (SIGIRR), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Single Ig IL-1-related receptor (SIGIRR), Truncated Now

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