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| Cat.No | ACP05496 | Target Name | SLC6A12 |
|---|---|---|---|
| Target Synonyms | betaine/GABA), member 12; Solute carrier family 6 (neurotransmitter transporter, member 12; Solute carrier family 6 member 12 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P48065 |
|---|
Uniprot Id
P48065
Target Species
Human
Target Name
SLC6A12
Target Full Name
Sodium- and chloride-dependent betaine transporter
Target Function
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A12 subfamily
Target Tissue Specificity
Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
Target Synonyms
Betaine/GABA transporter 1; BGT-1; BGT1; Gamma aminobutyric acid transporter; GAT2; Na(+)/Cl(-) betaine/GABA transporter; S6A12_HUMAN; Slc6a12; Sodium- and chloride-dependent betaine transporter; Solute carrier family 6 (neurotransmitter transporter), member 12; Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12; Solute carrier family 6 member 12
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