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Recombinant Human Sodium/nucleoside cotransporter 1 (SLC28A1), Truncated

ACP05413

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05413 Target NameSLC28A1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO00337
Background Information
  • Uniprot Id

    O00337

  • Target Species

    Human

  • Target Name

    SLC28A1

  • Target Full Name

    Sodium/nucleoside cotransporter 1

  • Target Function

    Sodium-dependent and pyrimidine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). Transports uridine, cytidine, thymidine, and nucleoside-derived drugs. Transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Concentrative nucleoside transporter (CNT) (TC 2.A.41) family

  • Target Tissue Specificity

    Expressed in kidney.

  • Target Synonyms

    CNT 1; CNT1; Concentrative nucleoside transporter 1; hCNT1; Na(+)/nucleoside cotransporter 1; S28A1_HUMAN; SLC28A1; Sodium-coupled nucleoside transporter 1; Sodium/nucleoside cotransporter 1; solute carrier family 28 concentrative nucleoside transporter member 1; Solute carrier family 28 member 1

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