Recombinant Human Solute carrier family 2, facilitated glucose transporter member 9 (SLC2A9), Truncated

Uniprot Id

Q9NRM0

Target Species

Human

Target Name

SLC2A9

Target Full Name

Solute carrier family 2, facilitated glucose transporter member 9

Target Function

Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or galactose.

Target Involvement

Hypouricemia renal 2 (RHUC2)

Target Subcellular Location

[Isoform 1]: Basolateral cell membrane; Multi-pass membrane protein.; [Isoform 2]: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.

Target Protein Families

Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily

Target Tissue Specificity

Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membra

Target Synonyms

glucose transporter 9; Glucose transporter like protein 9; Glucose transporter type 9; GLUT 9; GLUT-9; GLUT9; GLUTX; GTR9_HUMAN; Human glucose transporter like protein 9; SLC2A9; Solute carrier family 2 (facilitated glucose transporter) member 9; Solute carrier family 2 facilitated glucose transporter member 9; Solute carrier family 2 member 9; Solute carrier family 2 member 9 protein; Solute carrier family 2, facilitated glucose transporter member 9; UAQTL2; Urate voltage driven efflux transporter 1; URATv1

Target Background

This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.