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| Cat.No | ACP05817 | Target Name | SLC22A12 |
|---|---|---|---|
| Target Synonyms | Organic anion transporter 4-like protein; Renal-specific transporter; RST; S22AC_HUMAN; Slc22a12; Solute carrier family 22 member 12; Urate anion exchanger 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96S37 |
|---|
Uniprot Id
Q96S37
Target Species
Human
Target Name
SLC22A12
Target Full Name
Solute carrier family 22 member 12
Target Function
Major urate transporter involved in renal reabsorption of urate and helps to maintain blood levels of uric acid. Translocates urate over the apical membrane of proximal tubular cells in exchange for organic anions or chloride ions.
Target Involvement
Hypouricemia renal 1 (RHUC1)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Target Protein Families
Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family
Target Tissue Specificity
Detected in kidney (at protein level). Detected in fetal and adult kidney. Detected in epithelial cells of proximal tubules in renal cortex.
Target Synonyms
Organic anion transporter 4-like protein; Renal-specific transporter; RST; S22AC_HUMAN; Slc22a12; Solute carrier family 22 member 12; Urate anion exchanger 1
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