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Recombinant Human Solute carrier family 22 member 3 (SLC22A3), Truncated

ACP06716

Number
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Specifications


Cat.No ACP06716 Target NameSLC22A3
Target SynonymsSLC22A3; EMTH; OCT3; Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO75751
Background Information
  • Uniprot Id

    O75751

  • Target Species

    Human

  • Target Name

    SLC22A3

  • Target Full Name

    Solute carrier family 22 member 3

  • Target Function

    Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family

  • Target Tissue Specificity

    Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.

  • Target Synonyms

    SLC22A3; EMTH; OCT3; Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3

  • Target Background

    Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.

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