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| Cat.No | ACP14703 | Target Name | CDCA5 |
|---|---|---|---|
| Target Synonyms | CDCA5; CDCA5_HUMAN; Cell division cycle associated protein 5; Cell division cycle-associated protein 5; MGC16386; p35; Sororin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-252 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96FF9 |
|---|
Uniprot Id
Q96FF9
Target Species
Human
Target Name
CDCA5
Target Full Name
Sororin
Target Function
Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
Target Subcellular Location
Nucleus. Chromosome. Cytoplasm. Note=Associates with nuclear chromatin from S phase until metaphase and is released in the cytoplasm upon nuclear envelope breakdown.
Target Protein Families
Sororin family
Target Synonyms
CDCA5; CDCA5_HUMAN; Cell division cycle associated protein 5; Cell division cycle-associated protein 5; MGC16386; p35; Sororin
Target Background
Predicted to enable chromatin binding activity. Involved in double-strand break repair; mitotic sister chromatid segregation; and regulation of cell cycle process. Located in nucleoplasm.
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