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| Cat.No | ACP00756 | Target Name | SQLE |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 42-574aa | Mol Weight | 63.3 kDa |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14534 |
|---|
Uniprot Id
Q14534
Target Species
Human
Target Name
SQLE
Target Full Name
Squalene monooxygenase
Target Function
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
Target Subcellular Location
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Protein Families
Squalene monooxygenase family
Target Tissue Specificity
Detected in liver (at protein level).
Target Research Area
Cancer
Target Synonyms
SQLE; ERG1; Squalene monooxygenase; Squalene epoxidase; SE
Target Background
Enables FAD binding activity and squalene monooxygenase activity. Involved in lipid droplet formation; regulation of cell population proliferation; and sterol biosynthetic process. Located in intracellular membrane-bounded organelle. Is integral component of membrane.
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