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| Cat.No | ACP16671 | Target Name | SUSD4 |
|---|---|---|---|
| Target Synonyms | SUSD4; UNQ196/PRO222; Sushi domain-containing protein 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5VX71 |
|---|
Uniprot Id
Q5VX71
Target Species
Human
Target Name
SUSD4
Target Full Name
Sushi domain-containing protein 4
Target Function
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.
Target Subcellular Location
[Isoform 1]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.
Target Tissue Specificity
Isoform 3 is the predominant isoform in all tissues except cortex, cerebellum, kidney, and breast. Isoform 1 is found primarily in the esophagus and the brain.
Target Synonyms
SUSD4; UNQ196/PRO222; Sushi domain-containing protein 4
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