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| Cat.No | ACP23693 | Target Name | TLX1 |
|---|---|---|---|
| Target Synonyms | homeobox 1; T-cell leukemia/lymphoma protein 3; TCL 3 proto oncogene; TCL3; Tlx-1; TLX1; TLX1_HUMAN, included; T-cell acute lymphocytic leukemia, included; T-cell leukemia 3 gene; T-cell leukemia homeobox protein 1; T-cell leukemia | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-330 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P31314 |
|---|
Uniprot Id
P31314
Target Species
Human
Target Name
TLX1
Target Full Name
T-cell leukemia homeobox protein 1
Target Function
Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
Target Involvement
A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD.
Target Subcellular Location
Nucleus.
Target Synonyms
Homeo box 11 (T cell leukemia 3 associated breakpoint homologous to Drosophila Notch); Homeo box 11 (T cell lymphoma 3 associated breakpoint); Homeobox 11; Homeobox protein Hox 11; Homeobox protein Hox-11; Homeobox TLX-1; Hox-11; Hox11; MGC163402; OTTHUMP00000020816; Proto oncogene TCL 3; Proto-oncogene TCL-3; RGD1563655; T cell leukemia homeobox protein 1; T cell leukemia lymphoma protein 3; T-all, included; T-cell acute lymphocytic leukemia, included; T-cell leukemia 3 gene; T-cell leukemia homeobox protein 1; T-cell leukemia, homeobox 1; T-cell leukemia/lymphoma protein 3; TCL 3 proto oncogene; TCL3; Tlx-1; TLX1; TLX1_HUMAN
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