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Recombinant Human Teneurin-3 (ODZ3), Truncated

ACP11965

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11965 Target NameTENM3
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9P273
Background Information
  • Uniprot Id

    Q9P273

  • Target Species

    Human

  • Target Name

    TENM3

  • Target Full Name

    Teneurin-3

  • Target Function

    Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion. Required for proper dendrite morphogenesis and axon targeting in the vertebrate visual system, thereby playing a key role in the development of the visual pathway. Regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May also be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes.

  • Target Involvement

    Microphthalmia, isolated, with coloboma, 9 (MCOPCB9)

  • Target Subcellular Location

    Cell membrane; Single-pass membrane protein. Cell projection, axon.

  • Target Protein Families

    Tenascin family, Teneurin subfamily

  • Target Tissue Specificity

    Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nu

  • Target Synonyms

    FLJ10474; FLJ10886; KIAA1455; odd Oz Ten m homolog 3; odz odd Oz ten m homolog 3 (Drosophila); odz odd Oz ten m homolog 3; ODZ3 like protein; Protein Odd Oz ten m homolog 3; Protein Odd Oz/ten-m homolog 3; Ten 3; Ten M3; Ten-3; Ten-m3; TEN3_HUMAN; Tenascin M3; Tenascin-M3; Teneurin 3; Teneurin transmembrane protein 3; Teneurin-3; Teneurin3; tenm3; TNM3

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