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| Cat.No | ACP16730 | Target Name | TNS3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q68CZ2 |
|---|
Uniprot Id
Q68CZ2
Target Species
Human
Target Name
TNS3
Target Full Name
Tensin-3
Target Function
May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development.
Target Subcellular Location
Cell junction, focal adhesion.
Target Tissue Specificity
Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level). Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial
Target Synonyms
TEM 6; TEM6; TENS 1; TENS 3; TENS1; TENS3; TENS3_HUMAN; Tensin-3; tensin-like SH2 domain containing 1; Tensin-like SH2 domain containing protein 1; Tensin-like SH2 domain- containing protein 1; Tensin-like SH2 domain-containing protein 1; thyroid specific PTB domain protein; TNS 3; TNS3; TPP; Tumor endothelial marker 6
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