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Recombinant Human Threonine synthase-like 2 (THNSL2)

ACP15250

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15250 Target NameTHNSL2
Target SynonymsTHNSL2; Threonine synthase-like 2; TSH2; EC 4.2.3.-; Secreted osteoclastogenic factor of activated T-cells; SOFATFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-484
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ86YJ6
Background Information
  • Uniprot Id

    Q86YJ6

  • Target Species

    Human

  • Target Name

    THNSL2

  • Target Full Name

    Threonine synthase-like 2

  • Target Function

    Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate.; Potent inducer of osteoblastic production of IL6. May act to exacerbate inflammation and/or bone turnover under inflammatory conditions.

  • Target Subcellular Location

    [Isoform SOFAT]: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway.

  • Target Protein Families

    Threonine synthase family

  • Target Synonyms

    THNSL2; Threonine synthase-like 2; TSH2; EC 4.2.3.-; Secreted osteoclastogenic factor of activated T-cells; SOFAT

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